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Clinical data | |
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Pronunciation | / s ɪ l ˈ d ɛ n ə f ɪ l / sil- DEN -ə-fil |
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AHFS/Drugs.com | Monograph |
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Pregnancy category | AU: B1 US: B (No risk in non-human studies) |
Routes of administration | By mouth (tablets), IV |
ATC code | G04BE03 ( WHO ) |
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Pharmacokinetic data | |
Bioavailability | 41% (mean) [1] |
Protein binding | ~96% |
Metabolism | Liver: CYP3A4 (major route), CYP2C9 (minor route) |
Metabolites | N -desmethylsildenafil (~50% potency for PDE 5 ) |
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MUSE is available in four strengths, from to 1, mcg. When the penis is erect, a special band is secured around its base to retain the blood after the cylinder is removed.
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